Processing and quality control of DNA array hybridization data
نویسندگان
چکیده
منابع مشابه
Processing and quality control of DNA array hybridization data
MOTIVATION The technology of hybridization to DNA arrays is used to obtain the expression levels of many different genes simultaneously. It enables searching for genes that are expressed specifically under certain conditions. However, the technology produces large amounts of data demanding computational methods for their analysis. It is necessary to find ways to compare data from different expe...
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چکیده ندارد.
Improving DNA array data quality by minimising 'neighbourhood' effects.
Gene expression studies using cDNA arrays require robust and sensitive detection methods. Being extremely sensitive, radioactive detection suffers from the influence of signals positioned in each other's vicinity, the 'neighbourhood' effect. This limits the gene density of arrays and the quality of the results obtained. We have investigated the quantitative influence of different parameters on ...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2000
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/16.11.1014